Patent · US Active

Modified Cry3A toxins and nucleic acid sequences coding therefor

US8216806B2 · kind B2 · utility

3Cited by
10References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 2011
Grant dateJul 10, 2012
Priority date—
Expiry dateJul 25, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A40/146
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.