Pyridopyrazines and their use as modulators of kinases

US8217042B2 · kind B2 · utility

Assignee

• Zentaris GmbH · DE

Inventors

• Eckhard Claus · Frankfurt, DE
• Irene Seipelt · Offenbach, DE
• Eckhard Guenther · Maintal, DE
• Emmanuel Polymeropoulos · Frankfurt, DE
• Michael P. Czech · Frankfurt am Main, DE
• Tilmann Schuster · Großostheim, DE

Key dates

• Filing date: Nov 10, 2006
• Grant date: Jul 10, 2012
• Expiry date: Sep 23, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to pyrido[2,3-b]pyrazines of the general formulae (I) and (II), and to their preparation and use as medicaments, especially for the treatment of malignant disorders and other disorders based on pathological cell proliferations.