Patent · US Active

Topical composition comprising a dihydropyridine calcium antagonist

US8217062B2 · kind B2 · utility

1Cited by

1References

18Claims

0Family size

Assignee

Moberg Derma AB · SE

Inventors

Johan Engblom · Lund, SE
Birgitta Svensson · Malmö, SE
Anette Abrahamsson · Malmö, SE
Ake Lindahl · Malmö, SE

Key dates

Filing date	Aug 31, 2007
Grant date	Jul 10, 2012
Priority date	—
Expiry date	Aug 31, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A topical composition comprising a dihydropyridine calcium antagonist, a stiffening agent and a release modifier. The stiffening agent comprises a fatty alcohol, a fatty acid sorbitane ester, or a fatty acid glycerol ester, having a hydrocarbon chain containing 12 to 22 carbon atoms and having a melting point of about 45 to 750° C. The release modifier comprises a fatty alcohol, a fatty alcohol glycol ether, a fatty acid alkyl ester, a fatty acid glycerol ester, or a fatty acid sorbitane ester, having a hydrocarbon chain containing 12 to 18 carbon atoms and having a melting point of about −10 to 400° C. Use of such a composition for the treatment and/or prophylaxis of a dermal or mucosal disorder, preferably an anorectal disorder associated with high anal pressure or anal sphincter spasm.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.