Patent · US Active

2H-chromenes annelated at C5-C6 and methods of making and using thereof

US8217188B2 · kind B2 · utility

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1References
6Claims
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Assignee

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Key dates

Filing dateAug 4, 2009
Grant dateJul 10, 2012
Priority date
Expiry dateSep 25, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D309/32
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein are C5-C6 annelated naphthopyrans that possess at least one electron-withdrawing group. The compounds possess desirable properties such as increased fading kinetics. Also described herein are new methods for synthesizing 2H-chromenes annelated at C5-C6. The methods involve less stringent reaction conditions as well as provide increased reaction yields. The methods permit the synthesis of a wide variety of substituted naphthopyrans that can be temperature sensitive, which was not possible with previous synthetic routes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.