Gene products differentially expressed in cancerous cells

US8221983B2 · kind B2 · utility

Assignee

• Novartis Vaccines and Diagnostics, Inc. · US

Inventors

• Vivien Chan · Emeryville, US
• Jaime Escobedo · San Francisco, US
• Pablo Garcia · Emeryville, US
• Rhonda Hansen · Emeryville, US
• Joerg Kaufmann · Isenbüttel, DE
• Giulia C. Kennedy · San Francisco, US
• George Lamson · Moraga, US
• Edward Moler · Aliso Viejo, US
• Filippo Randazzo · San Bonifacio, IT
• Christoph Reinhard · Alameda, US
• Julie Sudduth-Klinger · Emeryville, US

Key dates

• Filing date: Mar 16, 2010
• Grant date: Jul 17, 2012
• Expiry date: Mar 16, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/136
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.