Patent · US Active

Methods of using substance P to promote healing of vascular wounds

US8222210B2 · kind B2 · utility

1Cited by
24References
3Claims
0Family size

Inventors

Key dates

Filing dateSep 9, 2009
Grant dateJul 17, 2012
Priority date—
Expiry dateSep 9, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L2300/602
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Healing of wounds in mammalian tissue may be enhanced by the application of certain neuropeptides, optionally in combination with known growth promoting hormones. Exemplary neuropeptides include tachykinins, such as Substance P, Substance K, and the like, as well as calcitonin gene-related peptides. The compositions may further include a polymeric delivery carrier and are utilized by applying to the site of the wound. Wounds may be vascular or avascular wounds. The compositions promote elaboration of cellular matrices and development of cellular attachment mechanisms in addition to stimulating cellular proliferation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.