Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
US8222286B2 · kind B2 · utility
7Cited by
18References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 16, 2010 |
| Grant date | Jul 17, 2012 |
| Priority date | — |
| Expiry date | Nov 16, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D261/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound of formula I:or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.