Histone deacetylase inhibitors and methods of use thereof
US8222451B2 · kind B2 · utility
4Cited by
11References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 25, 2010 |
| Grant date | Jul 17, 2012 |
| Priority date | — |
| Expiry date | Oct 25, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.