Patent · US Active

System and method for analyte sampling and analysis with hydrogel

US8224414B2 · kind B2 · utility

34Cited by
155References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 13, 2005
Grant dateJul 17, 2012
Priority date
Expiry dateAug 18, 2028

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/144444
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement an error correction method that corrects for sensor drift.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.