Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide sequences
US8226957B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 28, 2009 |
| Grant date | Jul 24, 2012 |
| Priority date | — |
| Expiry date | Mar 7, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55561
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of preventing and/or treating infection by a respiratory virus such as respiratory syncytial virus (RSV), particularly reducing infection and/or one or more symptoms of respiratory virus infection. A polynucleotide comprising an immunostimulatory sequence (an “ISS”) is administered to an individual which is at risk of being exposed to a respiratory virus, has been exposed to a respiratory virus or is infected with a respiratory virus. The ISS is administered without any antigens of the respiratory virus. Administration of the ISS results in reduced incidence and/or severity of one or more symptoms of respiratory virus infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.