Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof
US8227189B2 · kind B2 · utility
2Cited by
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26Claims
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Key dates
| Filing date | Feb 8, 2011 |
| Grant date | Jul 24, 2012 |
| Priority date | — |
| Expiry date | Feb 8, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular VT and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.