Rationally designed media for cell culture
US8232075B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 8, 2007 |
| Grant date | Jul 31, 2012 |
| Priority date | — |
| Expiry date | Sep 2, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/32
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to methods for rationally designing cell culture media for use in cell cultures, e.g., cell cultures employed in polypeptide production; cell culture media designed with the disclosed methods; methods of producing a polypeptide of interest, e.g., an antibody, using such media; polypeptides produced using the methods and media disclosed herein; and pharmaceuticals compositions containing such polypeptides. The rationally designed media contain a concentration of an amino acid that is calculated for use in cell mass, a concentration of the amino acid that is calculated for use in cell maintenance, and a concentration of the amino acid that is calculated for incorporation into the polypeptide of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.