Substituted benzimidazoles, benzothiazoles and benzoxazoles

US8232288B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Stefan Schunk · Aachen, DE
• Melanie Reich · Aachen, DE
• Michael Engels · Turnhout, BE
• Tieno Germann · Aachen, DE
• Jean De Vry · Stolberg, DE
• Ruth Jostock · Stolberg, DE
• Sabine Hees · Aachen, DE

Key dates

• Filing date: Jun 7, 2010
• Grant date: Jul 31, 2012
• Expiry date: Aug 18, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, pharmaceutical compostions containing these compounds and the use of these compounds for treating or inhibiting disorders or disease states mediated at least in part by bradykinin receptor 1 (BR1).