Patent · US Active

Chiral ligands, their preparation and uses thereof in asymmetric reactions

US8232399B2 · kind B2 · utility

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14Claims
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Assignee

Inventors

Key dates

Filing dateMar 2, 2007
Grant dateJul 31, 2012
Priority date
Expiry dateFeb 11, 2029

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel class of chiral ligands represented by a structure of Formula I:wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, C(O)R6, C(O)NHR6, Si(R6)3, benzyl and aryl; X is selected from the group consisting of OH, OR7, O-Prot and P(R7)2 where Prot represents a protecting group; and R6 and R7 are selected from the group consisting of hydrogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, phenyl, and aryl is disclosed herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.