Therapeutic delivery of carbon monoxide
US8236339B2 · kind B2 · utility
8Cited by
69References
11Claims
0Family size
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Key dates
| Filing date | Jan 27, 2006 |
| Grant date | Aug 7, 2012 |
| Priority date | — |
| Expiry date | Apr 12, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F17/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g. Fe and Ru. The carbonyl preferably has one or store ligands other than CO, such as amine acids, to modulate the CO release property and solubility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.