Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival
US8236506B2 · kind B2 · utility
2Cited by
12References
7Claims
0Family size
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Key dates
| Filing date | Sep 27, 2007 |
| Grant date | Aug 7, 2012 |
| Priority date | — |
| Expiry date | Apr 25, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/118
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the in vitro diagnosis of bronchopulmonary carcinoma, in particular of non-small cell bronchial carcinoma, characterized in that it comprises the stage of detecting, in a biological sample derived from a patient suspected to be suffering from said bronchopulmonary carcinoma, at least one of the major alternative transcripts of the KLK8 gene encoding kallikrein 8. This method is particularly useful for the survival prognostication of patients suffering from bronchopulmonary carcinoma.
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