Methods for sterilizing materials containing biologically active agents
US8236538B2 · kind B2 · utility
2Cited by
67References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 17, 2008 |
| Grant date | Aug 7, 2012 |
| Priority date | — |
| Expiry date | Sep 4, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/38
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Provided are methods for sterilizing a material comprising a biologically-active agent comprising irradiating said material with ionizing radiation at a dose of about 5 kGy to about 25 kGy while maintaining said material in an atmosphere comprising at least 95% by volume inert gas and at a temperature of about 4° C. or lower. Also provided are sterilized materials comprising a biologically-active agent, wherein said materials exhibit substantially the same amount of biological activity as a non-sterilized control.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.