Dimeric derivatives of artemisinin and application in anticancer therapy
US8236850B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Dec 22, 2008 |
| Grant date | Aug 7, 2012 |
| Priority date | — |
| Expiry date | Dec 22, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6561
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C═O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.