Patent · US Expired

System and method for carrying out fibre-type multiphoton microscopic imaging of a sample

US8237131B2 · kind B2 · utility

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6References
24Claims
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Key dates

Filing dateOct 21, 2005
Grant dateAug 7, 2012
Priority date
Expiry dateFeb 24, 2026

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG02B6/04
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A system for carrying out fibered multiphoton microscopic imagery of a sample (10) for use in endoscopy or fluorescence microscopy includes: a femtosecond pulsed laser (1, 2) for generating a multiphoton excitation laser radiation; an image guide (8) having a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating elements (4) for pre-compensating for dispersion effects of the excitation pulses in the image guide (8), these elements being situated between the pulsed laser and the image guide (8); scanning elements for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head (9) for focussing the excitation laser beam exiting the image guide in the sample (10).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.