Amphiphilic or lipophilic polar functionalized fullerenes and their uses

US8241648B2 · kind B2 · utility

Assignee

• Luna Innovations Incorporated · US

Inventors

• Zhiguo Zhou · Winston-Salem, US
• Robert P. Lenk · Lambertville, US
• Darren Kent MacFarland · Windsor, US
• Kenneth L. Walker · Semora, US
• Jing Zhang · Wantage, US
• Stephen R. Wilson · West Linn, US

Key dates

• Filing date: Mar 3, 2008
• Grant date: Aug 14, 2012
• Expiry date: Jul 28, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/007
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are synthetically modified fullerene molecules, wherein the fullerene is preferably ellipsoid in shape with an equatorial band and two opposing poles, comprising an adduct at one or both poles, at least one adduct being a hydrophobic chemical moiety capable of anchoring the fullerene on or in a lipid membrane.