Cell penetrating peptides for intracellular delivery of molecules
US8242081B2 · kind B2 · utility
54Cited by
2References
23Claims
0Family size
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Key dates
| Filing date | Dec 5, 2006 |
| Grant date | Aug 14, 2012 |
| Priority date | — |
| Expiry date | Jan 16, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.