Kinase substrates
US8242083B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 23, 2009 |
| Grant date | Aug 14, 2012 |
| Priority date | — |
| Expiry date | Jul 27, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/1205
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Tyrosine kinase substrates are described herein that are phosphorylated by many and diverse tyrosine kinases, and are chemically stable relative to co-polymers of poly-EY or poly-EAY having random molecular weights in the range of 20-50 kDa. Tyrosine kinase substrate peptides are provided according to embodiments described herein which include an isolated tyrosine kinase substrate peptide having molecular weight in the range of about 0.5 kD-10 kD. Tyrosine kinase substrate peptides are provided according to embodiments described herein having no more than 50 amino acids. The peptides include 2-25 phosphorylation modules and each phosphorylation module has 2-3 amino acid residues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.