Patent · US Active

Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents

US8242087B2 · kind B2 · utility

54Cited by

1References

37Claims

0Family size

Assignee

K.U. Leuven Research & Development · BE

Inventors

Olga Adelfinskaya · San Diego, US
Piet Herdewijn · Wezemaal, BE

Key dates

Filing date	Aug 27, 2009
Grant date	Aug 14, 2012
Priority date	—
Expiry date	Nov 19, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/20
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention relates to novel phosphate-modified nucleosides, and methods for producing them, being useful for the prevention or treatment of a viral infection in a mammal, and for preparing oligonucleotides by DNA/RNA polymerase-dependent amplification, e.g. PCR.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.