siRNA of NF-kB p105 for inhibiting cell proliferation and migration and a composition comprising same
US8242094B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Aug 22, 2008 |
| Grant date | Aug 14, 2012 |
| Priority date | — |
| Expiry date | Jan 1, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a siRNA which targets mRNA of the NF-Kappa B p105 gene to cause its degradation by RNAi induction. In addition, the present invention provides a pharmaceutical composition for the treatment of diseases associated with aberrant cell proliferation and migration, comprising the siRNA and delivery vehicle capable of intracellular delivery of the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.