Patent · US Active

1,3-benzoxazolyl derivatives as kinase inhibitors

US8242128B2 · kind B2 · utility

1Cited by

3References

18Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Wolfgang Stahle · Ingelheim am Rhein, DE
Alfred Jonczyk · Darmstadt, DE
Wilfried Rautenberg · Reinheim, DE

Key dates

Filing date	Sep 1, 2004
Grant date	Aug 14, 2012
Priority date	—
Expiry date	Mar 31, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compounds of formula 1, the production and use thereof as a medicament for the treatment of diseases, particularly tumours and/or diseases caused, mediated or propagated by angiogenesis. The compounds of formula 1 are effective inhibitors of tyrosin kinases, particularly TIE-2 and VEGFR, and Raf-kinases. (I)

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.