Processes for producing succinic acid from fermentation broths containing diammonium succinate

US8246792B2 · kind B2 · utility

Assignee

• BioAmber S.A.S. · CA

Inventors

• Olan S. Fruchey · Port Aransas, US
• Brian T. Keen · Charleston, US
• Brooke A. Albin · Charleston, US
• Nye A. Clinton · Hurricane, US
• Dilum Dunuwila · Okemos, US
• Bernard D. Dombek · Charleston, US

Key dates

• Filing date: Aug 19, 2011
• Grant date: Aug 21, 2012
• Expiry date: Aug 19, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P7/46
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Processes for making SA from either a clarified DAS-containing fermentation broth or a clarified MAS-containing fermentation broth that include distilling the broth under super atmospheric pressure at a temperature of >100° C. to about 300° C. to form an overhead that comprises water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt % water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion and a solid portion that is substantially pure SA; and separating the solid portion from the liquid portion. A method also reduces the broth distillation temperature and pressure by adding an ammonia separating and/or water azeotroping solvent to the broth.