Patent · US Active

Depsipeptides and their therapeutic use

US8247372B2 · kind B2 · utility

1Cited by
1References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 23, 2007
Grant dateAug 21, 2012
Priority date
Expiry dateNov 10, 2028

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds which are Spiruchostatin analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.