Patent · US Active

Crystalline irinotecan hydrochloride and methods for its preparation

US8247426B2 · kind B2 · utility

1Cited by

1References

12Claims

0Family size

Assignee

Antibioticos S.p.A. · ES

Inventors

Giovanni Pozzi · Carate Brianza, IT
Paolo Ghetti · Pioltello, IT
Gaetano Balsamo · Pioltello, IT
Ettore Negri · Firenze, IT
Marco Alpegiani · Milano, IT
Angelo Bedeschi · Milano, IT
Roberta Pizzocaro · Pioltello, IT

Key dates

Filing date	Nov 10, 2009
Grant date	Aug 21, 2012
Priority date	—
Expiry date	Aug 29, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a crystalline form of irinotecan hydrochloride (I) and processes for the preparation thereof from crude irinotecan hydrochloride or another polymorphic form of irinotecan. Said crystalline form is particularly suitable for industrial use, because it is easily filtered and possesses characteristics of high stability and purity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.