Benzamide derivatives useful as histone deacetylase inhibitors
US8247562B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Sep 10, 2010 |
| Grant date | Aug 21, 2012 |
| Priority date | — |
| Expiry date | Sep 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns a compound of the formula (I)wherein Ring A is heterocyclyl; m is 0-4 and each R1 is a group such as hydroxy, halo, trifluoromethyl and cyano; R2 is halo and n is 0-2; and each R4 is a group such as hydroxy, halo, trifluoromethyl and cyano; p is 0-4; and R3 is amino or hydroxy;or pharmaceutically-acceptable salts or in-vivo-hydrolysable ester or amide thereof;processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by histone deacetylase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.