MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma

US8252538B2 · kind B2 · utility

Assignees

• OHIO STATE UNIVERSITY · US
• The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · US
• Liver Cancer Institute and Zhongshan Hospital, Fudan University · CN

Inventors

• Carlo M. Croce · Philadelphia, US
• Xin Wang · Beijing, CN
• Anuradha Budhu · College Park, US
• Zhao-you Tang · Shanghai, CN

Key dates

• Filing date: Nov 1, 2007
• Grant date: Aug 28, 2012
• Expiry date: Dec 9, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/178
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Provided herein are methods and compositions for the diagnosis, prognosis and treatment of Hepatocellular carcinoma (HCC). Also provided are methods of identifying anti-HCC agents.