Pseudoinfectious flavivirus and uses thereof
US8252574B2 · kind B2 · utility
14Cited by
0References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 2007 |
| Grant date | Aug 28, 2012 |
| Priority date | — |
| Expiry date | Jul 23, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a replication-deficient pseudoinfective virus belonging to the Flaviviridae family that lack the capsid gene, where the replication-deficient pseudoinfective virus propagates only in cells expressing the capsid or capsid, prM and envelope protein of the flavivirus. The present also discloses the method of producing such viruses on a large scale and the use of these pseudoinfective viruses as vaccines for preventing diseases caused by infections of humans or animals by the viruses belonging to this family.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.