Methods of inhibiting the interaction between S100 and the receptor for advanced glycation end-products
US8252807B2 · kind B2 · utility
16Cited by
0References
5Claims
0Family size
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Key dates
| Filing date | Oct 8, 2008 |
| Grant date | Aug 28, 2012 |
| Priority date | — |
| Expiry date | Jan 27, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7068
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting an interaction between a S100 protein and the receptor for advanced glycation end-products is provided comprising administering to a subject a therapeutically effective amount of cromolyn, C5, or salt, hydrate, or solvate thereof. In some embodiments, the S100 protein is S100P. In some embodiments, the S100 protein is S100P. In addition, the present invention provides a method of treating a cancer comprising administering to a mammal a therapeutically effective amount of cromolyn, C5, or salt, hydrate, or solvate thereof. Additional methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.