Anti-sclerostin antibodies
US8257704B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Jun 21, 2011 |
| Grant date | Sep 4, 2012 |
| Priority date | — |
| Expiry date | Jun 21, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.