Antibodies against Clostridium difficile toxins and uses thereof

US8257709B2 · kind B2 · utility

Assignees

• University of Massachusetts · US
• MEDAREX INC. · US

Inventors

• Donna M. Ambrosino · Brookline, US
• Gregory Babcock · Marlborough, US
• Teresa J. Broering · Brookline, US
• Robert Graziano · Princeton, US
• Hector Javier HERNANDEZ · Canton, US
• Israel Lowy · Dobbs Ferry, US
• Robert Mandell · Moraga, US
• Deborah MOLRINE · Newton, US
• William D. Thomas · San Jose, US
• Hui Zhang · Jinan, CN

Key dates

• Filing date: Jul 31, 2009
• Grant date: Sep 4, 2012
• Expiry date: May 12, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S424/809
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antibodies that specifically bind to toxins of C. difficile, antigen binding portions thereof, and methods of making and using the antibodies and antigen binding portions thereof are provided herein.