Delivery of highly lipophilic agents via medical devices

US8257724B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Keith Cromack · Lake Bluff, US
• John L. Toner · Libertyville, US
• Sandra E. Burke · Libertyville, US
• Richard W. Krasula · Libertyville, US
• Lewis B. Schwartz · Lake Forest, US

Key dates

• Filing date: Mar 22, 2006
• Grant date: Sep 4, 2012
• Expiry date: Mar 17, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2300/45
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An apparatus and system for delivering a lipophilic agent associated with a medical device including: a medical device, a first lipophilic agent capable of penetrating a body lumen, wherein the transfer coefficients of the first lipophilic agent is by an amount that is statistically significant of at least approximately 5,000, wherein the first lipophilic agent is associated with the medical device, wherein the first lipophilic agent/medical device is placed adjacent to said body lumen, and wherein a therapeutically effective amount of the first lipophilic agent is delivered to a desired area within a subject. Furthermore, the invention relates to a method for improving patency in a subject involving placement of a medical device in a body lumen for treating and/or preventing adjacent diseases or maintaining patency of the body lumen.