Patent · US Active

Extracellular matrix compositions produced under hypoxic culture conditions

US8257947B2 · kind B2 · utility

9Cited by

23References

26Claims

0Family size

Inventors

Gail K. Naughton · Barre, US
Frank Ziegler · Encinitas, US
Mark Baumgartner · San Diego, US
Kyle Nickey · Vista, US

Key dates

Filing date	Jan 30, 2009
Grant date	Sep 4, 2012
Priority date	—
Expiry date	Jan 30, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/90
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to a method of producing compositions including embryonic proteins. The method includes culturing cells under hypoxic conditions on a biocompatible three-dimensional surface in vitro. The culturing method produces both soluble and non-soluble fractions, which may be used separately or in combination to obtain physiologically acceptable compositions useful in a variety of medical and therapeutic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.