Pin1-modulating compounds and methods of use thereof

US8258099B2 · kind B2 · utility

Assignees

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US
• Beth Israel Deaconess Medical Center, Inc. · US
• Salk Institute for Biological Studies · US

Inventors

• Kun Ping Lu · Newton, US
• Robert Suto · Shrewsbury, US
• Janusz Sowadski · Village of La Jolla, US
• Gunter Fischer · Hamburg, DE
• Joseph P. Noel · San Diego, US
• Mark A. Verdecia · San Diego, US

Key dates

• Filing date: Jul 15, 2005
• Grant date: Sep 4, 2012
• Expiry date: Sep 8, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to peptide modulators of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer or neurodegenerative disease.