Calcium phosphate complex for oral care applications, its preparation method, and compositions containing the same
US8263048B2 · kind B2 · utility
5Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2010 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Dec 21, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to a calcium phosphate complex and the composition containing the same for oral care applications, in which the calcium phosphate complex is formed by chelating the γ-polyglutamic acid (γ-PGA) with amorphous calcium phosphate (ACP). This complex can prevent crystallization of ACP and maintain its high solubility. The calcium phosphate complex has superior mucoadhesion properties, allowing it to remain in the mouth longer and offering effective buffering, by which dental caries can be alleviated and prevented.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.