Patent · US Active

Label free kinase assays and reagents

US8263377B2 · kind B2 · utility

1Cited by

10References

12Claims

0Family size

Assignee

Plexera, LLC · US

Inventors

Ronald P. Dudek · River Grove, US
Michael Cicirelli · Kirkland, US
Timothy Parker · Portage, US

Key dates

Filing date	Apr 2, 2008
Grant date	Sep 11, 2012
Priority date	—
Expiry date	Jul 13, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.