Controllably degradable hydrogel for culturing cells to produce three-dimensionally organized cells
US8263405B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Nov 24, 2006 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Jun 1, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/30
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
To provide a new reductive-stimuli-responsive degradable gel that allows any control of decomposition of the three-dimensional base material for cell culture and production of a completely biological three-dimensional cellular structure consisting only of cells and cells-produced extracellular matrix and that allows safe recovery of the cellular structure produced. A stimuli-responsive hydrogel, characterized by being produced by crosslinking a water-soluble polymer with a compound having a disulfide bond in the molecular chain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.