Non-natural sphingolipid analogs and uses thereof
US8263576B2 · kind B2 · utility
1Cited by
5References
4Claims
0Family size
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Key dates
| Filing date | Aug 15, 2007 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Jun 10, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5076
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure provides a composition useful for inhibiting caveolar endocytosis, plasma membrane microdomain formation, virus binding and infection, transmembrane signaling, and integrin function in cells. The composition is composed of non-natural analogs of sphingolipids, and may have applications in the treatment or amelioration of diseases associated with caveolar endocytosis, plasma membrane microdomain formation, transmembrane signaling, and integrin function. Methods for making and using the described composition are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.