Patent · US Active

Non-sedating antihistamine injection formulations and methods of use thereof

US8263581B2 · kind B2 · utility

16Cited by
24References
9Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 11, 2010
Grant dateSep 11, 2012
Priority date—
Expiry dateFeb 28, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are injectable compositions containing non-sedating or second and third generation antihistamines such as cetirizine/levocetirizine and methods of use thereof. Specifically, methods of treating acute allergic reactions including anaphylaxis with the compositions are disclosed. In certain embodiments, the injectable compositions are bioequivalent to currently marketed oral dosage forms. In other embodiments, the non-sedating or second and third generation antihistamine injectable formulations are therapeutically equivalent to diphenhydramine injectable formulations and/or are more effective than placebo. In other embodiments, a non-sedating antihistamine injectable composition is delivered by an autoinjector.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.