Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
US8263650B2 · kind B2 · utility
107Cited by
14References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 13, 2012 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Apr 13, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.