Patent · US Active

Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

US8263740B2 · kind B2 · utility

21Cited by

20References

19Claims

0Family size

Assignee

Ambrx, Inc. · US

Inventors

Zhenwei Miao · San Diego, US
Junjie Liu · San Diego, US
Thea Norman · San Diego, US
Russell Driver · Solana Beach, US

Key dates

Filing date	Feb 6, 2008
Grant date	Sep 11, 2012
Priority date	—
Expiry date	Jun 13, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides are disclosed. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. The non-natural amino acid polypeptides are further modified post-translationally. The non-natural amino acid polypeptides and modified non-natural amino acid polypeptides have many uses, including therapeutic, diagnostic, and other biotechnology uses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.