Dynamic characterization of particles with flow cytometry
US8264683B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 2, 2009 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Apr 29, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/0193
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Flow cytometry concepts are modified to enable dynamic characterizations of particles to be obtained using optical scattering data. Particles in flow will be introduced into a sample volume. Light scattered by a particle in the sample volume is collected and analyzed. What differentiates the concepts disclosed herein from conventional flow cytometry is the use of an acoustic source that is disposed to direct acoustic energy into the sample volume. As the particle passes through the sample volume, it responds to the acoustic energy, causing changes in the light scattered by the particle. Those changes, which are not measured during conventional flow cytometry, can be analyzed to determine additional physical properties of the particle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.