Patent · US Active

Method and apparatus for AC electrospray

US8267914B1 · kind B1 · utility

11Cited by
2References
41Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 18, 2004
Grant dateSep 18, 2012
Priority date
Expiry dateMar 31, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2037/0061
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, osteogenic or dermatological growth factors, bacteria, viruses, immobilized enzyme receptors and fluorescent particles for controlled release drug delivery, tissue or bone engineering, clinical or environmental field testing and as biosensors for clinical or drug monitoring. In addition, the present invention may be used to synthesize biodegradable fibers as bioscaffolds for tissue engineering, surgical sutures or medical gauze that enhance blood coagulation, and further may be encapsulated by other agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.