OCT4 and SOX2 with SV40 T antigen produce pluripotent stem cells from primate somatic cells
US8268620B2 · kind B2 · utility
25Cited by
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16Claims
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Key dates
| Filing date | Oct 23, 2009 |
| Grant date | Sep 18, 2012 |
| Priority date | — |
| Expiry date | Dec 10, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.