Pyrimidine derivatives and compositions as C-kit and PDGFR kinase inhibitors
US8268850B2 · kind B2 · utility
17Cited by
0References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 2008 |
| Grant date | Sep 18, 2012 |
| Priority date | — |
| Expiry date | Jan 31, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a novel class of pyrimidine derivatives, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.