Polymer two phase system and use thereof

US8268915B2 · kind B2 · utility

Assignee

• GE Healthcare Bio-Science AB · US

Inventors

• Hans O. Johansson · Lund, SE
• James Van Alstine · Stockholm, SE
• Rolf Hjorth · Uppsala, SE
• Karol Lacki · Uppsala, SE
• Emmanuel Macedo · Uppsala, SE
• Gunnar Malmquist · Uppsala, SE
• Jamil Shanagar · Uppsala, SE

Key dates

• Filing date: Jun 16, 2008
• Grant date: Sep 18, 2012
• Expiry date: May 6, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L33/10
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

The present invention relates to a liquid mixture comprising a first polymer, which is a poly(acid), a second polymer, which is a poly(ether), and at least one salt, wherein the molecular weight of the poly(acid) is in the range of 1000-100,000 Da. The second polymer is selected to be capable of forming immiscible aqueous phases in the presence of the poly(acid) and salt. The poly(acid) may be selected from the group consisting of poly(acrylic acid) and poly(methacrylic acid), and the second synthetic polymer may comprise ethylene oxide. The invention may be used for separation of biomolecules, cells or particles.