Method for diagnosing non-small cell lung carcinoma
US8273701B2 · kind B2 · utility
2Cited by
1References
1Claims
0Family size
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Key dates
| Filing date | Aug 14, 2006 |
| Grant date | Sep 25, 2012 |
| Priority date | — |
| Expiry date | Oct 14, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2216/11
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.